Medically reviewed by Alan Carter, Pharm.D. — created by Jill Seladi-Schulman, Ph.D. ~ above December 19, 2018

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Acetaminophen (Tylenol) and also ibuprofen (Advil) space both over-the-counter (OTC) medicines that can be provided to relieve pain.

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These drugs are 2 different varieties of pain relievers. Acetaminophen, sometimes provided as APAP, is its own type, if ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID).

Generally, it’s for sure to take it acetaminophen and ibuprofen together, yet you’ll want to pay close attention to how much you take of each medication.

The an essential to safely acquisition acetaminophen and also ibuprofen is knowing how much you’re acquisition at a time and also how often.

Acetaminophen dosage

The maximum safe dosage of paracetamol for anyone over the period of 12 is 4,000 milligrams (mg) per day. However even this lot can harm some people’s livers, so aim for no an ext than 3,000 mg per day.

For children under the age of 12, it’s best to inspect with their health care provider to determine the safest dose for your body weight.

Keep in psychic that numerous OTC medicines contain acetaminophen in a range of doses, usually 325 mg, 500 mg, or 650 mg.

Some examples of brand-name OTC medicines that might contain acetaminophen include:


Remember: once looking at labels, girlfriend might additionally see acetaminophen noted as APAP.

Ibuprofen dosage

Avoid taking much more that 1,200 mg of ibufrofen in a solitary day. OTC ibuprofen is often discovered in 200 mg pills. This equates to six pills a day. Still, friend should always verify just how much is in each pill.

Again, for children, it’s best to ask their healthcare provider about the safest dose for their weight.

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If you have actually prescription-strength ibuprofen, speak to her prescriber before mixing the with any kind of other medications, including acetaminophen.


The recommended boundaries for adults and children over 12 are:

3,000 mg per day the acetaminophen1,200 mg every day the ibuprofen

For youngsters under the period of 12, contact their medical care provider or describe the product label for dosage guidelines.

You can take ibuprofen and acetaminophen at the very same time. Just make sure to no take much more than the recommended dose.

Some civilization experience some stomach or abdominal pain when taking the two medicines together. In this case, it’s far better to alternating when you take it each medication.

For example, you could take ibuprofen first, followed by acetaminophen four hours later, and also then repeat this process as needed.

You could likewise alternate days. For example, if you take ibuprofen ~ above Monday, take acetaminophen on Tuesday and also so on.