Main distinction – Binary Fission vs Mitosis

Binary fission and also mitosis space two mechanisms provided in the asexual reproduction the organisms. A single organism is split into two daughter organisms during the binary fission. Binary fission is the asexual reproduction mechanism in prokaryotes. Mitosis is the vegetative cell department in eukaryotes. Asexual reproduction or the vegetative cell division is supplied for the growth, development, and replacement of cell in eukaryotes. The main difference in between binary fission and mitosis is the binary fission walk not kind a spindle apparatus whereas mitosis takes location through the spindle apparatus.

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This article looks at, 

1. What is Binary Fission – Mechanism, Types, Speed 2. What is Mitosis – Mechanism, Phases 3. What is the difference in between Binary Fission and also Mitosis


What is Binary Fission?

The division of a single organism into two daughter organisms is known as binary fission. Bacteria and also archaea choose prokaryotes usually exhibit binary fission as the cell department mechanism in your asexual reproduction. Part eukaryotic organelles prefer mitochondria also exhibit binary fission in stimulate to increase their number inside the cell. Prokaryotes save on computer a single, one chromosome in the genome. This DNA molecule is replicated before the cabinet division. While the parent cell pulls apart, replicated chromosomes space separated. Resultant two cells room genetically identical and have a potential to grow its original size in the species.


DNA replication is the an initial event in the procedure of binary fission. The solitary circular chromosome in the vegetative cell is strict coiled. It becomes uncoiled and then is replicated. Replicated two chromosomes move to opposing poles by an energy-dependent process. Then the cell boosts its length. Every the materials like ribosomes and also plasmids that the prokaryotic cell twin their number. The equatorial bowl constricts in order to separate the plasma membrane. A brand-new cell wall surface forms in between the separated cells. The department of the cytoplasm is recognized as cytokinesis. The two newly created cells contain about equal number of ribosomes, plasmids and other components. The volume that the cytoplasm is additionally approximately equal.


Figure 1: Binary Fission

Types that Binary Fission

Four types of binary fission can be identified.

Irregular binary fission – cytokinesis takes place in the perpendicular plane to the plane which karyokinesis has actually taken place. It occurs in amoeba.

Longitudinal binary fission – cytokinesis occurs along the longitudinal axis. This occurs in flagellates and Euglena.

Transverse binary fission – cytokinesis occurs follow me the transverse axis. It occurs in paramecium like protozoans.

Oblique binary fission – slope cytokinesis occurs together in ceratium.


Figure 2: Binary fission in Salmonella typhimurium bacterium


Binary fission is thought about as a quick process. Typically, one E. Coli cabinet at 37 °C divides every 20 minutes. The whole bacterial culture undergoes binary fission; therefore the time bring away by one bicycle is described as the doubling time. Some strains prefer Mycobacterium tuberculosis have slow copy time compared to E. Coli.

What is Mitosis

The vegetative cell department in eukaryotes is recognized as mitosis. Replicated genome is divided, creating two daughter nuclei complied with by the cytoplasmic department which may ultimately develop two cells from a single parent cell. The 2 cells space identical, bearing approximately equal variety of organelles and also cytoplasm. The mitotic step is called the M step of the cell cycle. Various types of mitosis have the right to be identified amongst organisms. During the “open” mitosis in animals, nuclear envelope is damaged down in order to separate the chromosomes. But in fungi, chromosomes different in the undamaged nucleus; this is called as “closed” mitosis.

Eukaryotes usage mitosis in your asexual reproduction, growth and also development, replacement of body cells and regeneration of human body parts. 


Mitotic division can be divided into four significant stages: prophase, metaphase, anaphase and the telophase. The chromosomes in the cell are replicated at the S phase of the interphase, prior to entering the M phase. Castle are additionally condensed and also attached come the spindle fibers. Proteins required for the cell department are synthesized throughout the interphase. Cellular materials including organelles are likewise doubled during the interphase.


During pre-prophase, the nucleus of the highly vacuolated plants migrates to the facility of the cell. Prophase is the first stage that the nuclear department in mitosis. At at an early stage prophase, the nuclear source disappears. The chromosomes are tightly coiled and also the development of the mitotic spindle is initiated in ~ the prophase. Chromosomes, containing 2 sister chromatids which are joined together at the centromere deserve to be visualized together thin, long, thread-like frameworks under the irradiate microscope. A pair the centrosomes shows up close come the nucleus i beg your pardon is surrounding by protein fibers, creating the microtubule spindle apparatus. Plants execute not possess a centrosome, i m sorry is the coordinating facility of microtubules. Thus, the formation of spindle apparatus is not necessary for the cell department in plants. 


Nuclear envelope disappears during the prometaphase of open mitosis. The kinetochore microtubules are attached to the kinetochores in chromosomal centromeres. The growth of the mitotic spindle takes location by communicating polar microtubules together. 2 centrosomes pull chromosomes in the direction of the the contrary poles by contracting the microtubules. Because of the tension, chromosomes space aligned in the equatorial key of the cell at the metaphase. Metaphase checkpoint guarantee the equal circulation of the chromosomes in ~ the equatorial plate.


During anaphase, sister chromatids space separated through the pulling tension generated by the centrosomes, developing two daughter chromosomes. This daughter chromosomes space pulled to the the contrary poles by further contracting microtubules. 


The contracted microtubules are loosened, lengthening the cell. A brand-new nuclear envelope is formed, enclosing 2 chromosome sets at the the contrary poles, reappearing 2 nuclei. 


Figure 3: Phases that Mitosis


The karyokinesis occurs in the M phase, followed by cytokinesis, the division of the cytoplasm, a process which is separated native the M phase. Plant cytokinesis is different from pet cytokinesis as result of the existence of a cell wall. In pet cells, a cleavage furrow is developed in order come pinch turn off the cytoplasm with the assist of contractile ring, developed at metaphase that karyokinesis. In plants, a cell plate is formed in the middle of the parental cell i beg your pardon matures come fuse v the existing cell wall. Both animal and plant cabinet cytokinesis are thrust by the vesicles comes from the Golgi apparatus. In most organisms, karyokinesis and also cytokinesis take ar separately.

Difference between Binary Fission and Mitosis


Binary Fission: Binary fission is the division of a single organism into two daughter organisms.

Mitosis: Mitosis is the vegetative cell division in eukaryotes. 

Type the Organism

Binary Fission: Binary fission largely takes ar in prokaryotes.

Mitosis: Mitosis takes ar in eukaryotes.


Binary Fission: Binary fission does no take place in organisms who have actually a nucleus.

Mitosis: Mitosis takes place in organisms who possess a nucleus.

Formation of the Spindle Apparatus

Binary Fission: A spindle apparatus is not formed during binary fission.

Mitosis: Eukaryotes possess a spindle apparatus throughout mitosis.

Doubling the Organelles

Binary Fission: Prokaryotes do not have actually organelles. However, ribosomes and also other cellular components are doubled before binary fission.

Mitosis: Organelles are doubled at the interphase in order come separate right into two cells.


Binary Fission: Asexual reproduction in prokaryotes is the duty of the binary fission.

Mitosis: Eukaryotes use mitosis because that asexual reproduction, growth and also development, replacement of body cells and regeneration human body parts.


Binary Fission: DNA is straight attached to the cabinet membrane during the binary fission.

Mitosis: DNA is attached to the spindle apparatus during the mitotic division.


Binary Fission: Binary fission is a much less reliable process, bring about increased variety of chromosomes in a cell.

Mitosis: Mitosis is corrected with metaphase checkpoint in bespeak to preserve a uniform chromosome number.


Binary Fission: Binary fission is a basic process.

Mitosis: Mitosis is comparatively complex than the binary fission.

Time Taken

Binary Fission: Binary fission is a fast process.

Mitosis: Mitosis takes part time due to its complexity.


Binary Fission: Binary fission takes location in bacteria and also eukaryotes like ameba, Hydra, and planaria.

Mitosis: Mitosis takes place in all animals including humans, all plants, and fungi.


Binary fission and also mitosis space two varieties of asexual reproduction mechanisms uncovered in prokaryotes and eukaryotes, respectively. Mitosis takes ar through number of phases, dividing the cell core of eukaryotic bio cells. It has actually a greater reliability due to the fact that corrections occur during metaphase checkpoint in stimulate to preserve a fixed chromosome number in the progeny. Hence, that is a time taking and more complex process contrasted to binary fission. Therefore, the key difference between binary fission and mitosis is your complexity.

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Reference:1. “Fission (Biology)”. N.p., 2017. Web. 8 Mar. 2017. 2.”Mitosis”. N.p., 2017. Web. 8 Mar. 2017.

Image Courtesy:1. “Binary Fission 2” through Ecoddington14 – (CC BY-SA 3.0) via Commons Wikimedia2. “Under a an extremely high magnification that 15000X, this colorized scanning electron micrograph (SEM) revealed the presence of a solitary Gram-ne” by CDC/ Bette Jensen via publicly Domain Files 3. “Mitosis Stages” through Ali Zifan – very own work; Used details from: Campbell biologic (10th Edition) by: woman B. Reece & Steven A. Wasserman.and (CC BY-SA 4.0) via Commons Wikimedia