Vyvanse, the brand name of Lisdexamfetamine dimesylate, is a Schedule II controlled substance that is used for the treatment of attention deficit hyperactivity disorder (ADHD) and moderate to severe binge eating disorder (BED) in adults. Like Adderall and Ritalin, some of the most common drugs used for ADHD treatment, Vyvanse is a central nervous system (CNS) stimulant with potential for dependence and abuse. Aside from Vyvanse half-life, this article will focus on some of the most commonly asked questions regarding Lisdexamfetamine dimesylate: “how long does Vyvanse last?”, “how long does it take to kick in?”, and “how long does Vyvanse stay in the system?”. The article will also be talking about ways of speeding up the process of getting it out of one’s system. Remember, though, that help is available to those suffering from Lisdexamfetamine dimesylate addiction or abuse. Recovery is very much possible.

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People who are worried about how long Vyvanse remains in the system need to know about the variables that can influence this to avoid overdose or other complications.


How Does Lisdexamfetamine Dimesylate Work?

The drug Vyvanse is used for the treatment of ADHD and binge-eating disorder (BED). Its basic component, Lisdexamfetamine dimesylate, becomes active only after absorption and conversion into d-amphetamine, its active ingredient. That is why this drug is a quintessential example of a “pro-drug.” Its effects become noticeable at the 1.5 or 2-hour mark, which is a bit slower compared to Adderall.

Lisdexamfetamine dimesylate is a stimulant medication that directly acts on the central nervous system (CNS). However, how it exactly acts therapeutically in ADHD and BED patients is not currently known. What is known is that it promotes and increases the release of dopamine and norepinephrine into the extraneuronal space to reduce the symptoms of ADHD in patients with the said disorder.

Lisdexamfetamine dimesylate has similar side effects with other stimulant drugs used for the treatment of ADHD, which include dry mouth, anxiety, trouble sleeping, nausea, vomiting, and loss of or decreased appetite, among others. The potential loss of or decrease in appetite may lead to weight loss, and although Vyvanse for weight loss has no approval, some may use it for that purpose without a doctor’s prescription, which is dangerous. Among Vyvanse side effects sexual adverse reactions are also common. Furthermore, without a doctor’s supervision, there is an increased risk for dependence, abuse, or addiction. To add to that, one may experience increased heart rate and blood pressure, serious cardiovascular reactions, psychiatric adverse reactions such as psychotic or manic symptoms, and serotonin syndrome.

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Variables Influencing How Long Vyvanse Remains In The System

People who are worried about how long Vyvanse remains in the system need to know about the variables that can influence this to avoid overdose or other complications. Usually, they are looking for ways to make Vyvanse wear off faster. However, not all variables that affect how long Vyvanse lasts in the system can be altered. While the half-life of Vyvanse has been determined through clinical tests, it is an average of all of those who were part of the trials. Some people eliminate the drug faster than others and vice versa. Factors that affect how long Vyvanse stays in the system include:

AgeFrequency of use – people who take Vyvanse more often will eliminate the drug slower than those who take it less oftenThe dose of the drug taken – the higher the dose one takes, the longer it will stay in one’s system

The factors discussed above are only but a part of a long list of factors that may affect how long drugs such as Lisdexamfetamine dimesylate will stay in the system. That said, the length of time it stays in the body is highly individual, and it’s nearly impossible to give an exact number of hours or days for which the drug will remain in one’s system.

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How To Speed Up System Cleaning

There are no specific methods guaranteed to get Lisdexamfetamine dimesylate out of the system faster than it naturally does, but there are methods that are used for flushing out drugs in general that can help. These include:

Drinking more water (about 2.7 liters per day for women and 3.7 liters per day for men) or using diuretics to urinate more frequently and thereby flush out the drug a little fasterConsuming antioxidant-rich drinks, 2-3 cups per day – things like tea, cranberry juice, lemon juice, and apple juiceAvoiding any alcohol until the drug is fully out of the system as it can delay excretionPerforming aerobic activities with the goal of sweating out the drugEating healthily so the body is not taxed with processing other toxic elementsIncreasing fiber intake to promote the excretion of the drug through feces

Anyone who is worried about passing a drug test for Lisdexamfetamine dimesylate is likely misusing the medication and in need of help, and not taking it for the treatment of actual health conditions like ADHD or BED. While looking for alternatives to Vyvanse is a good idea, the best course of action for those suffering from addiction or abuse is to discontinue use safely and let the body do the work – give it time to metabolize and eliminate it naturally. Additionally, seeking help and taking the route to recovery would be very beneficial not only to one’s body but also to their mental well-being. Drug rehabilitation centers can help those who abuse or are addicted to Lisdexamfetamine dimesylate or any other substance get clean and live a better life. There are many addiction treatment programs that can help those suffering from addiction to start their journey to recovery and most importantly, stay clean.


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