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Is Dr. Varon’s skin bleaching mechanism safe?

Sarah asks…I have actually some questions around Dr. Varon’s skin bleaching system. It offers 2% hydroquinone. Is it for sure to keep using?

First stop talk around skin bleaching actives. Hydroquinone, like plenty of other actives, HQ ,like plenty of skin lightening ingredients, is a phenolic compound. That means it contains a 6 carbon ring with an OH group attached. This structure permits it to inhibit melanin synthetic by acting together a substrate for tyrosinase.

You are watching: Horse hoof cream for human nails

Tyrosine, an amino acid, is acted ~ above by the enzyme tyrosine to kind melanin. This phenolic compounds “interrupt” this reaction by giving the tyrosine something rather to connect to. That method the tyrosine never makes melanin particles. Based on the research we’ve seen, nothing works much better than HQ – it’s taken into consideration the gold traditional for skin lightening. You have the right to find an ext details if you go back and inspect out illustration 35.

Is HQ safe? There have been studies that raised cancer concerns however they were based on oral or injected application and also there have actually been no clinical researches or instances of skin cancer concerned topical HQ use. Therefore, the International agency for research study on Cancer (IARC) considers hydroquinone as “not classifiable” regarding its carcinogenicity in humans. It can, however, reason a skin discoloring condition known as Och-ron-osis and that’s one of reasons the regulatory bodies in other countries have banned HQ for over the counter use. The has has to be prescribed by a physician which helps protect against the sort of long term abuse that have the right to lead to that long-term discoloration.

In the us The Food and also Drug management (FDA) has also proposed banning over-the respond to skin bleaching agents comprise hydroquinone yet as of right currently it’s still available.

This is a an extremely important point – the a myth that’s it’s “banned” in other countries, it’s yes, really just restricted to prescription use. Europe and also Asia currently allow hydroquinone at 2-5% concentration through prescription. The drug is valued an international but is regulation to protect against misuse and also bad formulations.

So, what around Dr Varon’s product? we were intrigued as soon as we read around his Skin Bleaching system which cases to be “the first and just skin care system to eliminate blemishes and also dark discolorations indigenous the skin.” It’s inconceivable how they deserve to make such a claim due to the fact that HQ is an end the counter drug. That provides me really suspicious.

The mechanism actually contains three products:

Step 1 Brightening lotion (1 oz.)
Step 2 Dermal therapy (1 oz.)Step 3 liquid Microdermabrasion (1 oz.)

The mechanism costs around 20 bucks which isn’t too bad until you establish you only gain one 1 oz tube of each product. But you don’t use them up in ~ the very same rate. You’re an alleged to usage the Brightening lotion double per day, the Dermal treatment you use as soon as a day and the liquid Microderm product you usage 2 or 3 times every week. So very quickly you’ll run out of the main product and you’ll need to buy the whole kit to get more. She probably better off buying an additional 2% HQ cream and also then using various other products.

Is that safe? Yes, aside from the pertains to we simply discussed. Is the the finest product to buy? more than likely not.

Active Ingredients: Hydroquinone (2%) Purpose: Bleach
Inactive Ingredients:
Step 1: Water, Isoproply Palmitate, Glycolic Acid, Cyclomethicone, Azelaic Acid, Kojic Dipalmitate, PEG-100 Stearate, Arbutin, Potassium Hydroxide, Cetyl Alcohol, Glyceryl Stearate, Myristyl Myristate, Sorbitol, Xanthan Gum, sodium PCA, Butylene Glycol, Simethicone, Magnesium Aluminum Silicate, Calcium Pantothenate. Extracts of: Chamomile, Comfrey, Echinacea, Fenugeek, Garlic, Lemon Peel, Propolis, Sage. White Oak Bark, Yarrow, Magnesium Ascorbyl Phosphate, Lactic Acid, Corn (Zea Mays) Oil (and) Retinyl Palmitate (Vitamin A Palmitate) (and) Cholecalciferol (Vitamin D3), Tocopheryl Acetate (Vitamin E Acetate), salt Hyaluronate, Phenoxyetanol, Trisodium EDTA, sodium Benzoate, Methylparaben, Propylparaben, Diazolidinyl Urea.
Step 2: Water, Glyceryl Stearate (and) PEG-100 Stearate, Propylene Glycol, Stearic Acid, Octyl Dimethyl PABA, Sorbitan Sesquioleate, Cetyl Acetate (and) Acetylated Lanolin Alcohol, Cetyl Alcohol, Mineral Oil, isopropyl Palmitate, Tocopheryl Acetate (Vitamin E Acetate), Dimethicone Xanthan Gum, Sorbic Acid, salt Sulfite, salt Bisulfite, sodium Benzoate, Methylparaben, Propylparaben, Diazolidinyl Urea.
Step 3: Aloe Barbadensis gel (Aloe Vera Gel), Propylene Glycol, isopropyl Palmitate, Sorbitol, Glyceryl Stearate, Stearic Acid, Cetyl Alcohol, Squalene, Laureth-4 PEG-100 Stearate, Glycolic Acid, Hydrolyzed Elastin, Lactic Acid, naval Collagen, Hydrolyzed Mucopolysaccharides, sodium PCA, street Cane Extract, Dimethicone, Polyethylene, Simethicone, Revitalin, Magnesium Aluminum Silicate, Xanthan Gum, Triethanolamine, Trisodium EDTA, sodium Benzoate, Methylparaben, Propylparaben, Imidazolidinyl Urea, Fragrance.

Is Hoof an equipment cream for equines really an excellent for your nails?

Kim’s question…Is Hoof maker for equines really great for finger nails? If it’s simply a good moisturizer can you recommend another product the would work as well?

I checked out the Hoof machine website and also found that it’s made through the same firm that renders Mane and also Tail. The template is the same across all these products and also it walk something choose this “we initially made these assets to take care of horses but amazingly human being put lock on your hair and also skin and also found out that they are incredible.”

It’s definitely an interesting backstory but when friend look in ~ the details claims they do for this Hoof an equipment product it’s really no that remarkable. Here’s what lock say:

“Now you can uncover the mystery behind luxuriously soft skin and beautiful nails. The exclusive mix of extensive protein enriched ingredients permits your hands and also body to achieve a natural feel when moisturizing dry and cracked skin. Originally occurred for steeds to moisturize dry, cracked, brittle hooves. Since applied to the hoof by human being hands, end time plenty of of those utilizing Hoofmaker top top their horses noticed dramatic innovation in the condition of their hands and also nails.”

Here are few of their specific claims:

Moisturizes dry, cracked skin top top hands, feet and other areas of the body
Fortifies nails and also protects them against damage, preserving their strength and also flexibilitySoftens and also conditions, deep penetrating rough, callused areasRestores critical nutrients and essential humidity to dry skin and nails in a greaseless formula
A manicure and pedicure in a bottle

I take it a look in ~ the ingredients and expected this to it is in just another typical moisturizing formulation. However, i was surprised to uncover that it uses some relatively unconventional ingredients.

In a traditional moisturizer you’d suppose to discover occlusive agents prefer petrolatum or mineral oil in addition to perhaps some hydrating agents prefer glycerin or hyaluronic acid or some other humectant. This product doesn’t use any of those occlusive agents. Rather its key ingredient is a chloride Quat, particularly distearyldimonium chloride.

This approach actually makes sense due to the fact that it’s designed for nails fairly than skin. Skin deserve to be character language by locking in moisture however nails room a tiny bit different. So, fairly than using an occlusive , the main ingredient is a fat chloride quat, distearyldimonium chloride. I’ve seen this provided before since it has a confident charge and also can stick to skin. The product likewise appears come contain a great percentage the glycerin which should aid bind humidity to the nail.

Coconut oil is additionally high on the ingredient list. We know how coconut oil is good for hair because it can penetrate into the keratin protein of hair I’ve never seen any type of data that mirrors it deserve to penetrate right into nails in a similar method but certainly has potential.

And ultimately it consists of a lactate salt i beg your pardon is great for pond in the same with lactic mountain is good.

The only ingredient that appears to be missing that can make this product even much better is some type of urea.

So all points being considered this is substantially various than a usual skin was to increasing lotion. Yet to Kim’s concern then how deserve to you discover a comparable product that has actually a different scent. We did find a pair of other products that use a similar matrix the ingredients. Right here they are.

Curel’s Youth-Defense moisture LotionWater, Glycerin, Distearyldimonium Chloride, isopropyl Palmitate, Cetearyl Alcohol, Petrolatum, Butyrospermum Parkii (Shea Butter), Salvia Officinalis (Sage) leaf Extract, Ascorbyl Palmitate (Vitamin C), Tocopheryl Acetate (Vitamin E), Hydrolyzed Collagen, Hydrolyzed Elastin, Corn starch Modified, Dimethicone, Polypropylene, Beeswax (Apis Mellifera), Capric/Caprylic Stearic Triglyceride, Glyceryl Dilaurate, Alumina, Stearic Acid, Acacia Gum (Acacia Senegal) Extract, Phenoxyethanol, Gelatin, Disodium EDTA, DMDM Hydantoin, Propylparaben, Methylparaben, Titanium Dioxide, Fragrance

Gold Bond ultimate Restoring Skin treatment LotionWater, Hydroxyethyl Urea, Glycerin, Dimethicone, Jojoba Esters, Petrolatum, Glyceryl Stearate, Distearyldimonium Chloride, Aloe Barbadensis leaf Juice, Cetearyl Alcohol, Methyl Gluceth 20, Behentrimonium Methylsulfate, Cetearyl Alcohol, Butyrospermum (Shea Butter) Extract, Ubiquinone, Ceramide complicated 2, Palmitoyl Oligopeptide, Cocodimonium Hydroxypropyl Hydrolyzed Rice Protein, Niacinamide, Tocopheryl Acetate, Magnesium Ascorbyl Phosphate, Retinyl Palmitate, PEG 10 Rapeseed Sterol, Hydrolyzed Collagen, Polysorbate 60, Stearamidopropyl PG Dimonium Chloride Phosphate, Propylene Glycol, Steareth 21, Diazolidinyl Urea, Fragrance, Methylparaben, Hydrolyzed Jojoba Esters, EDTA (Ethylenediamine-Tetra-Acetic Acid), Propylparaben, Butylene Glycol, C12 15 Alkyl Benzoate, Tribehenin, Potassium Hydroxide

Hoof an equipment IngredientsWater/Aqua/Eau, Distearyldimonium Chloride, Cetyl Alcohol, Stearyl Alcohol, Glycerin, Cocos Nucifera (Coconut) Oil, Stearamidopropyl Dimethylamine Lactate, Cetearyl Alcohol, Polysorbate 60, Steareth-20, Glycine Soja (Soybean) Oil, DMDM Hydantoin, Fragrance (Parfum), Methylparaben, Lanolin, PEG-150 Stearate, Propylparaben, Hydrolyzed Collagen Protein, PEG-25 Castor Oil, salt Chloride, Allantoin, Olea Europaea (Olive) Fruit Oil, Yellow #5 (CI 19140), Yellow #6 (CI 15985), Benzyl Benzoate, Benzyl Salicylate, Citronellol, Geraniol, Hexyl Cinnamal, Butylphenyl Methylpropional, Limonene, Linalool, Hydroxyisohexyl-3-Cyxlohexene Carboxaldehyde

Is Hexinol the latest anti-aging miracle?

Priyasha says…I to be curious around this “Hexinol” modern technology range the the ROC brand has actually been marketing. They to speak it’s a brand brand-new anti-aging an innovation they discovered. What precisely this hexinol technology is, and if in fact its simply a stunner anti-aging “ingredient” gimmick or if over there is something an extensive here.

Here’s some information from the website for RoC which, through the way, is owned by J&J…

Here space some particular claims lock make:

Restore elasticity and firmnessImprove radianceHydrate dry skinSmooth the look of good lines and also wrinklesLighten the look at of discoloration

Even despite they say the Hexinol works “in a different method than other anti-aging ingredients” these room pretty standard claims that sound similar to most various other anti-aging ingredients!

We reviewed the ingredient lists because that a couple of the ROC products and found that Hexinol is really simply their trademarked surname for the ingredient Hexylresorcinol.

(BTW, scientists must have actually HATED this due to the fact that of the name. First of all hexinol sounds practically exactly like “hexanol” i beg your pardon is a various chemical, the alcohol do from hexane, which has nothing to execute with anti-aging. Second, the “hex” name renders it sound prefer magic.)

So, what the hell is hexylresorcinol? You could be familiar with it due to the fact that its been offered for a long time as an antiseptic in products like mouthwashes and throat lozenges. Yet recently it’s also been presented to have skin lightening properties.

I don’t know if HR was discovered by J&J since other suppliers use this stuff, most notably Clarins. It’s sold by a company named Sytheon and I don’t think there’s anything proprietary about it. Their profession is Synovia HR and their website does file three clinical tests that suggest the molecule has anti-aging properties:

First, in vitro trial and error shows HR inhibits the manufacturing of melanin (36% intercellular and 75% extracellular.) However, the test didn’t compare it to anything so i don’t recognize what that means.

Second, another in vitro check measured inhibition that the enzyme that convert tyrosine come melanin. This to be done versus other proven skin lightening actives and the results confirmed that HR is far better than hydroquinone, licorice and also kojic acid.

Third is a human clinical research comparing HR in ~ 0.5% to hydroquinone in ~ 2%. The tests measured two kinds of results.

The an initial result verified a higher ITA which represents Individual Typography Angle. A greater ITA indicates better skin brightening. HR verified an advancement that’s around equivalent come HQ but since it just took 0.5% HR to obtain the same result at 2% HQ they obtain to case that HR is “4x much more effective than HR.” That seems a little bit misleading come me due to the fact that it implies that it provides skin 4 time lighter 보다 HQ and also that’s no the instance at all.

The second an outcome was labeled simply as “% development in skin brightening” which doesn’t tell united state anything around how the test to be done. In any type of event, HR did around as well as HQ.

When feather for proof of exactly how an ingredient functions you never ever want to solely rely on information from the supplier therefore we uncovered that HR has actually been reviewed by other evidence-based beauty, beauty blogs prefer the cosmetics Cop and Truth in Aging. Here’s what Paula Begon says…

“Hexylresorcinol is a fabricated ingredient that has actually been displayed to have skin lightening ability in cabinet cultures however there is very minimal research about it on skin. It is mostly an antioxidant, antiseptic and also anesthetic.”

She likewise cited a study released in a 2013 edition of journal of drugs in Dermatology and also said that…

“This study is frequently quoted together saying it worked far better than or and 4% hydroquinone but 4 weeks is not long enough to judge that and again, and also this was not about hexylresorcinol chin .”

Finally, the website truth in Aging says…

”HR’s capacity to target pathways in the skin that bring about hyperpigmentation has propelled it into the skin lightening ingredient category. There is also thought that Hexylresorcinol has more benefits together well, consisting of an capability to alleviate the illustration of fine lines and also wrinkles, rise protection against UVB and also UVA rays, and also improve the skin’s barrier versus pollution and also sun exposure.”

Unfortunately, the attach to a resource of their details didn’t work-related so i’m not certain where that details came from. (But I check out that the supplier’s website makes some of these exact same claims.)

What’s the bottom line around HR? It appears to be a promise ingredient however we can not use seen enough evidence to suggest that it’s far better than various other proven alternatives. If you’re in search of something brand-new to try and you don’t mind the price, then i don’t see any kind of reason no to give Hexinol a chance.

Ingredient lists for ROC productsWater, Glycerin, Cetyl Alcohol, Nylon 12, Dimethicone, Ethylhexyl Hydroxystearate, Ethylhexyl Palmitate, Glyceryl Stearate, Hexyldecyl Stearate, PEG 100 Stearate, Sorbitan Stearate, Phenoxyethanol, Mica, sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Butyrospermum Parkii (Shea) Butter, Hexylresorcinol, Titanium Dioxide, Isohexadecane, Fragrance, Methylparaben, Polysorbate 80, Acrylates/C10 30 Alkyl Acrylate Crosspolymer, Disodium EDTA, Tocopheryl, Sucrose Cocoate, Ascorbic Acid, Panthenol, salt Hydroxide, Saccharomyces Cerevisiae Extract

Water, Glycerin, Cetyl Alcohol, Nylon 12, Dimethicone, Ethylhexyl Hydroxystearate, Ethylhexyl Palmitate, Glyceryl Stearate, Hexyldecyl Stearate, PEG 100 Stearate, Sorbitan Stearate, Phenoxyethanol, Mica, salt Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Butyrospermum Parkii (Shea) Butter, Hexylresorcinol, Titanium Dioxide, Isohexadecane, Fragrance, Methylparaben, Polysorbate 80, Acrylates/C10 30 Alkyl Acrylate Crosspolymer, Disodium EDTA, Tocopheryl, Sucrose Cocoate, Ascorbic Acid, Panthenol, salt Hydroxide, Saccharomyces Cerevisiae Extract

iTunes Reviews

Abcfg says… Informative, funny, and relevant!

Kublakaan says….I love their nerdy, scientific, non-biased way of explaining the good and bad of beauty products. They obviously have a firm grasp on statistical analysis, data analysis, and obviously chemistry. Despite all the hard science, they’re is easy to understand, and even funny. I’m a much wiser and selective consumer now that I can better spot the marketing traps that beauty companies use to milk us of our money!

Improbable Products

I read an post on 6 crazy spa treatments but they just weren’t crazy enough. Therefore I made up one of mine own. You guys have to guess i m sorry is the fake.

Chicken soup saunaOne Spa chain in the southern US will certainly soak friend in warm chicken soup i m sorry is affluent in fats and also proteins that nourish the skin.

Fire facialThis Chinese treatment supplies a cool burn alcohol fire to stimulate skin and fight indications of aging.

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Butter bath In Ethiopian spas, females moisturize skin through rubbing butter almost everywhere your body and also then melt it away v smoke.